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相关实验视频

Updated: Jul 2, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
11:24

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation

Published on: July 4, 2015

在小鼠中出现异常的灰化效应,小鼠接受了较高剂量的X射线.

D B GALBRAITH, H B CHASE

    Science (New York, N.Y.)
    |January 12, 1962
    PubMed
    概括
    此摘要是机器生成的。

    暴露于X射线会延迟小鼠毛发的生长,并扰乱黑色素细胞的分布,导致过早的白色变白. 这种效应主要是由于激光敏感毛囊的失活引起的,而不是组织的替代.

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    Greying of hair. II. Response of individual hairs in mice to variations in x-radiation.

    Journal of morphology·2014
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    The influence of oxygen and peroxides on the response of mammalian cells and tissues to ionizing radiations.

    Progress in nuclear energy. Series 6 Biological sciences·2014
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    Studies on an anophthalmic strain of mice; associated cranial nerves and brain centers.

    The Journal of comparative neurology·2010
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    Greying induced by x-rays in the mouse.

    Genetics·2010
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    Biological evaluation of 20 million volt roentgen rays; decoloration of hair in mice.

    The American journal of roentgenology and radium therapy·2010
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    Genetic studies of the mouse mutations mahogany and mahoganoid.

    Genetics·1997

    科学领域:

    • 皮肤病学和辐射生物学

    背景情况:

    • 毛囊是对外部刺激敏感的复杂结构.
    • 黑色素生成,黑色素的生产过程,对于头发的颜色定性至关重要.

    研究的目的:

    • 为了研究不同剂量的X射线对小鼠毛囊的影响.
    • 了解辐射引起的头发变白和生长中断背后的机制.

    主要方法:

    • 对小鼠毛囊暴露于特定剂量的X射线 (1100-1700r).
    • 观察和分析头发生长,黑色素生成和黑色素细胞分布.

    主要成果:

    • 1200,1300和1400r的X射线剂量导致头发增长的延迟.
    • 观察到早期的黑色素生成和受损的黑色素细胞分布.
    • 头发发白的反应被归因于放射敏感毛囊的不活化.

    结论:

    • 辐射暴露显著影响毛囊功能和颜色.
    • 毛囊无活化是辐射引起的头发变白的主要机制.
    • 这些发现对了解状体单位的辐射损伤有意义.
    关键词:
    头发/辐射影响辐射效应/实验性辐射效应

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