相关实验视频
Updated: Jul 26, 2026

06:23
A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
Published on: January 12, 2017
概括
雌性大鼠的排卵可以被巴比酸盐阻断,如果在关键窗口中给药. 下垂体排卵激素释放的关键时期发生在下午2点至4点之间.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 神经内分泌学神经内分泌学
- 研究中的动物模型.
背景情况:
- 淋巴激素的使用可以诱导雌性大鼠的排卵.
- 排卵的时间是生殖过程中的关键因素.
- 了解荷尔蒙调节是生殖科学的关键.
研究的目的:
- 为了研究在接受淋巴激素治疗的老鼠中阻断排卵的潜力.
- 为了确定垂体排卵激素释放的关键时间窗口.
- 为了确定巴比酸盐给药对排卵时间的影响.
主要方法:
- 在32天的雌性大鼠中,使用孕马的血清性腺激素进行治疗.
- 在预期排卵前一天的下午,巴比图酸盐在不同时间被施用.
- 排卵在第二天被评估以确定封锁.
主要成果:
- 排卵可以通过巴比酸盐的管理来阻止.
- 封锁取决于巴比酸剂的时间.
- 确定下垂体排卵激素释放的关键时期是在下午2点至4点之间.
结论:
- 下垂体排卵激素的释放是时间敏感的,发生在特定的下午窗口内.
- 在这个关键时期的药理干预可以防止排卵.
- 这一发现对了解排卵的神经内分泌控制有意义.
相关概念视频
Hormonal Regulation of the Menstrual Cycle
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Ovarian Cycle
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Hormonal Control of the Ovarian Cycle
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...

