患有高除门的患者的临床特征和结果. 一个多中心的研究研究
A E Epstein1, K A Ellenbogen, K A Kirk
1Division of Cardiovascular Disease, University of Alabama, Birmingham 35294.
Circulation
|October 1, 1992
概括
患有高除门的患者面临更高的风险,但植入式心脏转换器-除器 (ICD) 植入可以改善存活率. 抗心律失常药物使用可能导致值升高,这强调了需要优化ICD治疗的必要性.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 电子生理学 电子生理学
背景情况:
- 使用可植入心脏转换器-除器 (ICD) 进行成功的除需要超过除门的冲击.
- 在受影响的患者中确定高除门和结果的预测因素至关重要.
研究的目的:
- 确定预测升高 défibrillation 值的临床特征.
- 描述患有高除门的患者的结果.
主要方法:
- 对12个中心的1946名患者病历进行了回顾性分析.
- 确定了90名患有除值≥25J的患者 (4.6%).
- 具有和没有ICD植入的患者之间的结局的比较.
主要成果:
- 患有高除门的患者主要是男性,射出率降低,冠状动脉疾病患病率高.
- 抗节律障碍药物的使用,特别是阿米奥达龙,是常见的.
- 与没有ICD相比,ICD植入显著改善了2年和5年生存率 (81%与2年36%相比;5年73%与<32个月).
结论:
- 抗心律失常药物的使用可能与升高的除门有关.
- 在患有高值的患者中,即使使用ICD,心律失常死亡仍然是一个显著的风险.
- 通过强有力的测试来优化ICD贴片的放置,可以提高除安全边缘.
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