心脏手术后的和心律失常的管理. 一个安慰剂控制的,双盲的,随机的试验
M R England1, G Gordon, M Salem
1Department of Anesthesia, New England Medical Center Hospital, Tufts University School of Medicine, Boston, Mass.
JAMA
|November 4, 1992
概括
的管理有效地减少了心室节律失常和心脏手术后心脏指数的改善. 这项研究强调了在治疗术后并发症方面的好处,特别是在低血症患者中.
科学领域:
- 心血管外科心血管外科
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
背景情况:
- 低磁血症在心脏手术患者中很常见.
- 手术后的低磁性血症与增加的发病率有关.
研究的目的:
- 评估在减少术后发病率和死亡率方面的疗效.
- 评估对心脏功能和手术后心律失常的影响.
主要方法:
- 随机,双盲,安慰剂对照试验,涉及100名接受心脏手术的患者.
- 患者在手术期间接受化输液或安慰剂.
- 监测了手术后的结果,包括心律失常和心脏指数.
主要成果:
- 接受治疗的患者患上术后心室失律症的数量显著减少 (16%vs34%).
- 与低磁性病患者相比,正常磁性病患者出现的超心室失律症较少.
- 的使用导致术后心脏指数较高 (2.8比2.5L/分钟/m2).
结论:
- 的管理减少了心室节律失常,并改善了早期的术后心脏指数.
- 手术后的低磁性血症与心室节律失常的增加和长时间的机械通风有关.
- 在治疗心脏手术患者的低血症和相关并发症方面有好处.
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