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相关概念视频

Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

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Vasodilatory response of the coronary arteries after Kawasaki disease: evaluation by intracoronary injection of isosorbide dinitrate.

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Multiple genetic alterations in human carcinogenesis.

Environmental health perspectives·1992
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Establishment of a highly sensitive and specific exon-trapping system.

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Anti-tolA antibody in non-A, non-B chronic liver disease.

Fukuoka igaku zasshi = Hukuoka acta medica·1992
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Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2'-deoxyguanosine and its phosphate esters.

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Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

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Local signals, systemic decline.

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The mechanics of liver regeneration.

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Computing in a memory with physics.

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Retraction.

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相关实验视频

Updated: Jul 6, 2026

Detecting Anastasis In Vivo by CaspaseTracker Biosensor
20:16

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

多阶段致癌:一个1992年前景.

T Sugimura1

  • 1National Cancer Center, Tokyo, Japan.

Science (New York, N.Y.)
|October 23, 1992
PubMed
概括
此摘要是机器生成的。

癌症仍然存在 日本

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Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
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科学领域:

  • 在瘤学瘤学.
  • 营养科学 营养科学
  • 毒理学 毒理学 毒理学

背景情况:

  • 在日本,癌症是死亡的主要原因.
  • 癌症发病率模式的转变表明与西方化的饮食习惯和生活方式存在相关性.
  • 异环胺是肉和鱼中发现的变异性化合物,涉及致癌.

研究的目的:

  • 调查饮食因素,特别是异环胺在日本人口癌症发展中的作用.
  • 探索西方化的生活方式变化与不断变化的癌症发病率之间的关系.
  • 根据多因素致癌的情况,重新评估当前的癌症风险评估方法.

主要方法:

  • 分析饮食模式及其与癌症发病率的关联.
  • 在通常消费的食品中识别和量化异环胺.
  • 对日本癌症趋势的流行病学数据的审查.

主要成果:

  • 有证据表明,西方饮食模式与癌症风险增加之间存在联系.
  • 异环胺被确定为重要的致癌物,有助于致癌.
  • 致癌的多阶段性质涉及到遗传变化的积累.

结论:

  • 饮食因素,包括煮熟食品中的异环胺,在癌症发展中起着至关重要的作用.
  • 向西方模式的生活方式的改变与日本癌症发病率的上升有关.
  • 对相互作用因素的全面理解对于完善癌症风险评估策略至关重要.