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相关概念视频

Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
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Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...

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相关实验视频

Updated: Jun 24, 2026

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
12:21

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Published on: November 27, 2016

19S抗体的抑制通过7S抗体的合成

K SAHIAR, R S SCHWARTZ

    Science (New York, N.Y.)
    |July 24, 1964
    PubMed
    概括

    治疗6 - 默卡波普林阻断了7S抗体的发展,而引入7S抗体减少了子中的19S抗体. 这表明7S抗体水平在免疫反应期间调节19S抗体合成.

    科学领域:

    • 免疫学 免疫学 免疫学
    • 生物化学 生物化学

    背景情况:

    • 抗体的产生涉及不同的免疫球蛋白类,包括19S (IgM) 和7S (IgG) 抗体.
    • 从19S转变为7S抗体的产生是适应性免疫反应的一个关键方面.

    研究的目的:

    • 在子中研究19S和7S抗体合成之间的调节关系.
    • 为了确定6 - 默卡普托普林对抗体类转换的影响.
    • 探索已经存在的7S抗体对19S抗体水平的影响.

    主要方法:

    • 子被免疫牛肉马球蛋白.
    • 用6 - 默卡普托普林进行治疗,以评估其对抗体转化的影响.
    • 在动物中进行了特定的反应性同源7S抗体的静脉注射,这些动物发展出幽默反应.
    • 随着时间的推移,对抗体度 (19S和7S) 进行了监测.

    主要成果:

    • 治疗6 - 墨卡波氨酸抑制了19S抗体转化为7S抗体.
    • 给予7S抗体导致现有的19S抗体迅速减少.
    • 经过一段时间的延迟,7S抗体的合成恢复到正常水平.
    • 结果表明一个反机制,其中7S抗体度影响19S抗体的产生.
    关键词:
    抗体形成 抗体形成实验室研究实验室研究玛环球蛋白质 (Gamma globulin) 是一种这就是MERCAPTOPURINE.药理学 在药理学方面.蛋白质的新陈代谢过程子子是什么意思

    更多相关视频

    Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)
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    Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)

    Published on: September 17, 2019

    Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells
    06:53

    Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells

    Published on: June 2, 2022

    相关实验视频

    Last Updated: Jun 24, 2026

    Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
    12:21

    Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

    Published on: November 27, 2016

    Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)
    09:39

    Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)

    Published on: September 17, 2019

    Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells
    06:53

    Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells

    Published on: June 2, 2022

    结论:

    • 7S抗体的度似乎调节了19S抗体的合成.
    • 这一发现为复杂的免疫调节提供了洞察力.
    • 了解这种相互作用可能会对调节免疫反应产生影响.