Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Action Potentials01:41

Action Potentials

Overview
Action Potential01:14

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Action Potential01:14

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Permeability of the Giant Axon of Dosidicus gigas to Calcium Ions.

The Journal of general physiology·2009
Same author

Effect of monovalent-divalent cation exchange on the swelling of polyacrylate hydrogels in physiological salt solutions.

Biomacromolecules·2001
Same author

Osmotic swelling of polyacrylate hydrogels in physiological salt solutions.

Biomacromolecules·2001
Same author

Catecholamines-evoked cytosolic Ca2+ rise in endothelial cells from bovine adrenal medulla.

Molecular and cellular biochemistry·2000
Same author

Rapid structural changes in nerve fibers and cells associated with their excitation processes.

The Japanese journal of physiology·1999
Same author

Repetitive mechanical responses of the amphibian skin to adrenergic stimulation .

The Japanese journal of physiology·1998

相关实验视频

Updated: Jul 14, 2026

Large Scale Zebrafish-Based In vivo Small Molecule Screen
07:03

Large Scale Zebrafish-Based In vivo Small Molecule Screen

Published on: December 31, 2010

智利巨型鱼的细胞内透作用

I TASAKI, M LUXORO

    Science (New York, N.Y.)
    |September 18, 1964
    PubMed
    概括

    巨型鱼的轴突在注入富含的溶液时表现出超过160mV的作用电位. 富含的溶液还产生了超越Nernst方程预测的动作潜力,维持神经传导超过一个小时.

    科学领域:

    • 神经科学是一个神经科学.
    • 细胞生物学 细胞生物学
    • 生物物理学的生物物理.

    背景情况:

    • 了解神经脉冲产生背后的离子机制在神经科学中至关重要.
    • 纳恩斯特方程根据离子度预测了膜潜力,但实验偏差突出了复杂的细胞过程.

    研究的目的:

    • 为了研究细胞内离子度和鱼巨型轴突中的动力潜能生成之间的关系.
    • 在不同的内部离子条件下探索神经传导的行为.

    主要方法:

    • 孤立的智利巨型鱼轴突的细胞内 perfusion 与富含或的盐溶液.
    • 在不同的液化合物下记录动力电位和静止电位.
    • 观察到的作用电位与Nernst方程预测的理论值的比较.

    主要成果:

    • 在海水中谷氨酸 perfusion 时,经常观察到超过 160 mV 的作用电位.
    • 富含的酸 (酸或酸盐) 产生的作用潜力高于Nernst方程的预测.
    • 神经传导持续了一个多小时,即使内部和外部度相同.

    结论:

    • 细胞内离子组成显著影响鱼巨型轴突中的动能振幅.
    关键词:
    轴突 (AXONS) 是指轴突 (AXONS) 的一个部分.电力物理学的电力学.实验室研究实验室研究摩卢斯卡 (Mollusca) 是一种类动物.表演 表演 表演是一种.酸盐的使用方法

    更多相关视频

    Oral Intubation of Adult Zebrafish: A Model for Evaluating Intestinal Uptake of Bioactive Compounds
    04:33

    Oral Intubation of Adult Zebrafish: A Model for Evaluating Intestinal Uptake of Bioactive Compounds

    Published on: September 27, 2018

    Manipulation of Gene Function in Mexican Cavefish
    07:01

    Manipulation of Gene Function in Mexican Cavefish

    Published on: April 22, 2019

    相关实验视频

    Last Updated: Jul 14, 2026

    Large Scale Zebrafish-Based In vivo Small Molecule Screen
    07:03

    Large Scale Zebrafish-Based In vivo Small Molecule Screen

    Published on: December 31, 2010

    Oral Intubation of Adult Zebrafish: A Model for Evaluating Intestinal Uptake of Bioactive Compounds
    04:33

    Oral Intubation of Adult Zebrafish: A Model for Evaluating Intestinal Uptake of Bioactive Compounds

    Published on: September 27, 2018

    Manipulation of Gene Function in Mexican Cavefish
    07:01

    Manipulation of Gene Function in Mexican Cavefish

    Published on: April 22, 2019

  • 从Nernst方程观察到的偏差表明有活跃的传输机制或其他调节离子流量的因素.
  • 鱼巨型轴突在改变的离子梯度下保持神经导电方面表现出了显著的弹性.