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Updated: Jun 15, 2026

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An Isolated Working Heart System for Large Animal Models
Published on: June 11, 2014
随机比较慢性心房动的外部和内部心脏转变
Circulation
|November 1, 1992
概括
在治疗心房动 (AF) 方面,内部心脏转换比外部心脏转换更有效. 这两种方法都显示出相似的AF复发率,当外部方法失败时,内部心脏转换是一种更安全的替代方案.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 前庭动 (AF) 的管理通常涉及心脏转变.
- 与外部心脏转换相比,内部心脏转换的有效性仍在研究中.
- 之前的研究表明,内部冲击对AF转换有潜在的益处.
研究的目的:
- 在慢性AF患者中,前性地比较内部与外部心脏转换的疗效和安全性.
- 为了评估长期的成功率和AF的复发在两个心脏转变技术后.
- 评估阿米奥达龙在心转动后维持鼻节律中的作用.
主要方法:
- 一项随机研究涉及112名患有慢性AF的患者.
- 患者通过心房电极导管接受外部心脏转换 (300-360 J) 或内部心脏转换 (200-300 J).
- 所有患者在心脏转变前和之后都接受了低剂量阿米奥达龙治疗,随访1年.
主要成果:
- 与外部心脏转换 (67%) 相比,内部心脏转换的疗效 (91%) 显著更高 (p=0.002).
- 体重是与心脏转变成功相关的唯一变量.
- AF复发率在各组之间是相似的; 37%的人在1年内保持了鼻节律. 并发症是最小的.
结论:
- 在慢性AF患者中,内部心脏转移优于外部心脏转移来恢复鼻节律.
- 这两种方法相对安全,AF复发率相似.
- 当外部心脏转换对耐火性AF无效时,建议进行内部心脏转换.
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