在肺循环中冷保存的同种移植管道的故障
D C Cleveland1, W G Williams, A J Razzouk
1Division of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
Circulation
|November 1, 1992
概括
在先天性心脏病患者的肺循环重建中,冷保存的同种移植管显示出令人失望的长期功能. 在15%的患者中,需要重新手术,主要是由于形狭窄症.
科学领域:
- 心血管外科心血管外科
- 儿童心脏病学 儿童心脏病学
- 生物材料科学 生物材料科学
背景情况:
- 先天性心脏病需要复杂的手术干预.
- 肺循环的重建是手术管理的一个关键方面.
- 为此目的,使用了冷保存的同种移植管道.
研究的目的:
- 评估冷保存的同种移植门管道的长期疗效和结果.
- 评估肺循环中与这些导管相关的功能性能和并发症率.
主要方法:
- 在1985年至1990年间,对219名接受心脏外导管安置的患者进行了回顾性分析.
- 肺和大动脉同移植的比较.
- 随访评估患者的存活率,重新手术率和重新手术的指示.
主要成果:
- 11%的住院死亡率;14个晚期死亡,主要是由于心脏形.
- 15%的医院幸存者因管道相关问题需要重新手术.
- 在5年内,保险学自由度为55%,缩是最常见的迹象.
结论:
- 肺循环中冷保存的同种移植管的长期功能是不理想的.
- 由于狭窄而导致的高重复手术率表明耐用性受到限制.
- 对替代重建材料的进一步研究是有必要的.
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