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mitra annulus 的刚性环固定不会损害正常狗心中的左心室缩功能
S C Rayhill1, L J Castro, M A Nizyporuk
1Department of Cardiovascular and Thoracic Surgery, Stanford University School of Medicine, Calif.
Circulation
|November 11, 1992
概括
刚性额外外除整形固定不损害左心室 (LV) 缩功能. 这项研究没有发现全球或区域LV机制的显著变化,固定与可移动的米特拉环在狗中.
科学领域:
- 心血管生理学心血管生理学
- 心脏机械学 心脏机械学
- 手术研究的研究.
背景情况:
- 之前的研究表明,中腹除术环可能会对左心室 (LV) 缩性能产生负面影响.
- 这项研究调查了刚性心肌环状固定对LV缩功能的影响.
研究的目的:
- 为了测试这个假设,刚性心肌环状固定改变了LV缩功能.
- 为了评估全球和区域LV收缩力学的负载不敏感指数.
主要方法:
- 全球和区域LV系统力学机制的比较,对10只狗进行了严格固定和自由移动的米特拉 annuli.
- 使用了卡蒂尔-爱德华兹无效整形环,并评估了诸如末缩弹性和预加载可招募中风等参数.
- 在不同的环状况下测量了大动脉流量,LV压力和LV尺寸.
主要成果:
- 在严格固定和自由移动的米特拉环状状况之间,在总体LV缩力学上没有观察到显著的差异.
- 区域LV的缩性表现也没有显著的变化,与刚性部环状固定.
- 关键参数包括末缩室弹性和纤维弹性保持不变.
结论:
- mitra annulus 的刚性固定不会改变整体 LV 缩功能.
- 区域LV的缩功能也不受刚性部环状固定的影响.
- 这些发现适用于麻醉后的,胸部开放的,心室正常的狗.
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