相关实验视频
Updated: Jun 14, 2026
09:12
A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
Published on: April 27, 2019
在婴儿和儿童心脏移植后心室体积的增长
V R Zales1, K L Wright, A J Muster
1Division of Cardiology, Children's Memorial Hospital, Chicago, IL 60614.
Circulation
|November 11, 1992
概括
儿童心脏移植接受者表现出正常的心脏功能和心室生长. 这项研究证实,心脏移植支持儿童健康的左心室体积扩张.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心脏移植手术是什么心脏移植手术
- 儿科心脏手术 儿科心脏手术
背景情况:
- 儿童心脏移植的存活率正在改善.
- 有限的数据存在于心室生长和心脏功能移植后在儿科患者.
研究的目的:
- 为了评估血液动力学,左心室 (LV) 体积和心室功能,在儿科心脏移植接受者中进行序列测试.
- 评估心脏移植后婴儿和儿童的心脏功能和生长.
主要方法:
- 在移植后的3年内,每年都会进行连续心脏导管.
- 测量了血液动力学参数,LV体积和射出分数.
- 进行了心脏内膜活检,以评估慢性排斥.
主要成果:
- 随着患者的生长,左心室终端透支体积增加,保持预测值.
- 射出分数保持在正常预测范围之内.
- 没有发现慢性排斥或加速冠状动脉动脉样硬化的证据.
结论:
- 儿童心脏移植接受者表现出正常的血液动力学和LV功能.
- 心脏移植促进了正常的LV体积增长,即使有免疫抑制和脱皮.
相关概念视频
01:16Chambers of the Heart
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
01:27Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...