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在心脏手术后的儿童体外膜氧化
S C Raithel1, D G Pennington, E Boegner
1Division of Cardiovascular Surgery, St. Louis University Medical Center, MO 63110-0250.
Circulation
|November 1, 1992
概括
身体外膜氧化 (ECMO) 为患有耐火性心脏切除术后心力衰竭的儿童提供了心肌恢复的机会. 这种生命支持可以使重症儿科心脏手术患者的生存成为可能.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管外科心血管外科
- 关键护理医学 关键护理医学
背景情况:
- 65名儿童 (1天-14岁) 在心脏手术后在1982-1991年间接受了体外膜氧化 (ECMO).
- 44% (67.7%) 的儿童从ECMO中断奶,其中23人 (35.4%) 幸存下来.
研究的目的:
- 为了确定预先ECMO预测小儿心脏手术患者存活率的因素.
- 评估ECMO在促进心肌恢复和存活方面的有效性.
主要方法:
- 对29个ECMO前变量的分析,包括诊断,年龄,性别,血液气体数据,血液动力学和功能.
- 统计分析以确定生存的预测因素.
- 对幸存者的长期随访.
主要成果:
- 在幸存者中观察到手术前的下部系统性心室缩短分数.
- 透析的需要和ECMO支持的持续时间是生存的重要预测因素.
- 在18名长期幸存者中,有17人 (平均随访37.5个月) 处于纽约心脏协会功能类I.
结论:
- 在大多数患有耐火性心脏切除术后心力衰竭的儿科患者中,ECMO有助于心肌恢复.
- ECMO为选择的儿科心脏手术患者提供了生存益处,否则他们无法生存.
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