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使用Jarvik-7人工心脏进行分期心脏移植的生存预测
A T Kawaguchi1, C Cabrol, A Pavie
1Chirurgie Cardiovasculaire, Hôpital de la Pitié, Paris, France.
Circulation
|November 1, 1992
概括
预测接受Jarvik-7人工心脏作为通往心脏移植的桥梁的患者的生存率至关重要. 基于术前因素的评分系统准确地确定了成功结果的合适候选人.
科学领域:
- 心血管外科心血管外科
- 医疗器械 医疗器械
- 移植医学 移植医学
背景情况:
- 机械循环辅助装置 (例如,Jarvik-7人工心脏) 用作通往心脏移植的桥梁.
- 这些设备的使用使得捐赠者的可用性和医疗费用受到压力.
- 确保安全有效的设备使用至关重要.
研究的目的:
- 用Jarvik-7人工心脏进行分阶段心脏移植的患者的生存预测模型的开发.
- 确定影响移植成功的关键手术前因素.
主要方法:
- 用Jarvik-7人工心脏对58例病例进行了回顾性审查.
- 单变量和多变量分析以确定显著的手术前因素.
- 基于六个因素的评分系统的开发:移植排斥/术后心力衰竭,接受者的身高,身体表面积,高白血,体重和年龄.
主要成果:
- 开发了一个评分系统 (每个因子1-4分).
- 总得分小于4的患者表现出高的生存率 (93%的灵敏度).
- >= 4的得分表明移植成功率和出院率较低 (70%的特异性).
结论:
- 在分阶段心脏移植中,手术前的因素有效地预测了移植性和存活率.
- 患者的选择和手术前的条件对于成功使用Jarvik-7作为移植的桥梁至关重要.
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