概括
基质子调节胚胎大脑中的乳酸脱酶活性. 低度的歇斯顿诱导活性,而高度通过改变蛋白质合成来抑制活性.
科学领域:
- 生物化学 生物化学
- 发展生物学 发展生物学
- 分子生物学分子生物学
背景情况:
- 基因组是参与DNA包装的关键蛋白质.
- 基因调节对于细胞分化和功能至关重要.
研究的目的:
- 调查组织蛋白在胚胎小大脑发育中的调节作用.
- 为了确定不同 histone 度对酶活性的影响.
主要方法:
- 培养胚胎的脑组织.
- 添加不同度的希斯.
- 测量乳酸脱酶 (LDH) 的活性.
- 评估蛋白质合成.
- 测量乙胆 Esterase (AChE) 的活性.
主要成果:
- 低 histone 度诱导了乳酸脱酶活性.
- 高 histone 度抑制了乳酸脱酶的活性.
- 希斯对LDH的影响通过改变蛋白质合成来调节.
- 乙胆雌激酶的活性没有受到组织蛋白或蛋白质合成抑制剂的影响.
结论:
- 基质子在胚胎的神经系统中起着主要的调节作用.
- 激素度是决定其调节效果的关键因素.
- 在这种系统中,LDH是由基质子调节的关键酶,而ACHE不受影响.
关键词:
乙烯基胆的利害关系增加.在ACTINOMYCIN中使用.氨基酸是氨基酸的组成部分.大脑酵素学化学 化学是什么一个子胚胎它们是DNA DNA DNA DNA.胚胎是一个胚胎.实验室研究实验室研究希斯托尼斯 (Histones) 是一种乳酸盐脱生成过程药理学 在药理学方面.蛋白质的新陈代谢过程在PUROMYCININ中,我们可以使用PUROMYCIN.组织培养 组织培养更多相关视频
08:06Preparation of Synaptic Plasma Membrane and Postsynaptic Density Proteins Using a Discontinuous Sucrose Gradient
Published on: September 3, 2014
07:36Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
相关概念视频
Stomach pH Regulation
The human body carefully regulates the internal pH of different organs to maintain homeostasis. For example, while the blood plasma maintains a neutral pH of 7, the stomach lumen has an acidic pH of 1.5 - 3.5. The low pH of stomach lumen helps kill pathogens in the food and break down complex food molecules.
The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
pH Regulation in Cells
pH plays a critical role in maintaining normal cellular activities. It helps maintain the structure and function of various proteins, dictates the charge on cellular membranes, and is crucial for metabolic reactions inside the cell. Moreover, cells use the energy from the proton motive force to generate ATP.
Cytosolic pH
Under physiological conditions, the cytosolic pH is slightly more acidic than the extracellular pH. However, cells must prevent further acidification of their cytosol to...
Cytosolic pH
Under physiological conditions, the cytosolic pH is slightly more acidic than the extracellular pH. However, cells must prevent further acidification of their cytosol to...
Gut-Brain Axis
The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...
