概括
在 rhesus 子中,红核的电刺激可靠地触发了复杂的行为. 这种反应在睡眠期间和通过甲被抑制,但不是通过自主阻断剂.
科学领域:
- 神经科学是一个神经科学.
- 灵长类动物的行为
- 发动机控制器的控制器
背景情况:
- 红核是大脑干中关键结构,参与运动控制.
- 了解它的功能需要研究在直接刺激的反应中唤起的行为.
- 以前的研究还没有完全阐明红核刺激引起的特定行为序列.
研究的目的:
- 研究长期,间歇性,无线电控制的红核脑内刺激对 rhesus 子的行为影响.
- 为了确定睡眠和药物剂对唤起的行为序列的影响.
主要方法:
- rhesus 子受到红核的脑内电极刺激,每分钟5秒,白天和晚上,长达14天.
- 在刺激期间,自发睡眠期间,以及在服用普罗玛,阿特罗平,雷吉丁和印鲁罗后,观察到行为反应.
主要成果:
- 红核刺激可靠地唤起了一系列行为,包括双脚运动,登,发声和社交互动.
- 在自发睡眠期间,刺激只会引起轻微的头部运动;醒来后,整个序列恢复.
- хлорпромазин 显著抑制唤起的行为序列,类似于睡眠.
- 自主阻断剂 (阿特罗平,雷吉丁,英杜罗尔) 对引起的反应的影响很小.
结论:
- 红核在启动和协调复杂的运动行为和 rhesus 子的社会互动中起着至关重要的作用.
- 唤起的行为序列取决于动物的兴奋状态,在睡眠期间被抑制.
- хлорпромазин 的抑制作用表明多巴胺基通路在调解红核唤起的行为中的潜在参与.
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