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Updated: Jun 19, 2026

Evaluation of Mammary Gland Development and Function in Mouse Models
08:51

Evaluation of Mammary Gland Development and Function in Mouse Models

Published on: July 21, 2011

鼠标的生长 哺乳腺在单层培养后在活体中生长

C W DANIEL, K B DEOME

    Science (New York, N.Y.)
    |August 6, 1965
    PubMed
    概括

    在实验室培养的小鼠乳腺细胞失去了专门的特征. 在移植到脂肪中时,一些细胞再生了正常的乳腺外生,而另一些细胞则形成了具有培养诱导异常的腺体.

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    科学领域:

    • 发育生物学 发展生物学
    • 组织工程是组织工程.
    • 细胞生物学 细胞生物学

    背景情况:

    • 主要小鼠乳腺组织在细胞培养中失去专门的特征.
    • 了解组织再生和培养诱导的变化至关重要.

    研究的目的:

    • 研究培养的小鼠乳腺细胞的再生潜力.
    • 为了识别由细胞培养和随后的组织再生引起的异常.

    主要方法:

    • 主要小鼠乳腺组织在体外培养.
    • 培养细胞植入无腺体的乳腺脂肪中.
    • 分析了再生的乳腺外生和腺体.

    主要成果:

    • 培养的乳腺细胞没有保留专门的特征.
    • 植入后发生了乳腺外生长的成功再生.
    • 一些再生的腺体表现出各种由培养引起的异常.

    结论:

    • 乳腺细胞培养可以导致专业功能丧失.
    • 植入允许再生,但培养引起的异常可能会持续存在.
    • 这种模型系统对于研究组织发育和培养效应非常有价值.
    关键词:
    细胞分裂 细胞分裂实验室研究实验室研究的母亲的母亲美国的米饭.组织培养 组织培养

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    Last Updated: Jun 19, 2026

    Evaluation of Mammary Gland Development and Function in Mouse Models
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    Evaluation of Mammary Gland Development and Function in Mouse Models

    Published on: July 21, 2011

    Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland
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    Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland

    Published on: December 1, 2015

    Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
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    Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation

    Published on: February 15, 2018