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毒素残留物决定T细胞受体Vβ结合特异性

M J Irwin1, K R Hudson, J D Fraser

  • 1Department of Immunology, Scripps Research Institute, La Jolla, California 92037.

Nature
|October 29, 1992
PubMed
概括

葡萄球菌肠毒素与MHCII类结合并激活T细胞. 肠毒素中的两个关键氨基酸残留物决定了特定的T细胞受体相互作用,区分了与Vβ3和Vβ11结合的肠毒素A和E.

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