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Updated: Jul 8, 2026

Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications
10:12

Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications

Published on: April 21, 2023

稳定的染料-DNA间复合物作为高灵敏度光检测试剂.

A N Glazer1, H S Rye

  • 1Department of Molecular and Cell Biology, University of California, Berkeley 94720.

Nature
|October 29, 1992
PubMed
概括

新的光标签是使用多化配体和双链DNA创建的. 这些多染色体标签为先进的光测试提供了新的应用.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...