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在MHC编码的蛋白酶子单元通常不需要处理由MHC I类分子结合的

D Arnold1, J Driscoll, M Androlewicz

  • 1Division of Tumor Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115.

Nature
|November 12, 1992
PubMed
概括

这项研究表明,蛋白酶体对于抗原处理并不必不可少. 即使没有关键的蛋白酶组分 (LMP2和LMP7),细胞仍然可以通过主要基因相容性复合物I类分子呈现.

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