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The Role of Actin and Myosin in Non-muscle Cells01:10

The Role of Actin and Myosin in Non-muscle Cells

Actin and myosin or actomyosin filaments also play a significant role in cells other than those involved in muscle contraction (which occurs within the sarcomere of muscle cells). The mechanism of non-muscle cell contractile bundles was first observed in Dictyostelium and Acanthamoeba. In non-muscle cells, two bundles are commonly found: stress fibers and actomyosin adherence belts. These contractile bundles are smaller and less organized than the ones found in muscle cells. They  are held...
Condensins02:15

Condensins

Condensins are large protein complexes that use ATP to fuel the assembly of chromosomes during mitosis. They transform the tangled, shapeless mass of post-interphase DNA into individualized chromosomes by compacting, organizing, and segregating chromosomal DNA.
The plant and animal cells contain two types of condensin complexes—condensin I and condensin II. Both complexes have five subunits: two SMC (Structural Maintenance of Chromosomes) subunits, a kleisin subunit, and two HEAT-repeat...
The Contractile Ring02:15

The Contractile Ring

Contractile rings are composed of microfilaments and are responsible for separating the daughter cells during cytokinesis. Contractile ring assembly proceeds along with other cell cycle events; however, very few mechanistic details are known about the timing and coordination of the contractile rings with the cell cycle.
A small GTPase, RhoA, controls the function and assembly of the contractile ring. RhoA belongs to the Ras superfamily of proteins. The activation of formins by RhoA promotes...
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
Smooth Muscle Contraction01:25

Smooth Muscle Contraction

Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...

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相关实验视频

Updated: Jul 9, 2026

A Microfluidic Technique to Probe Cell Deformability
09:47

A Microfluidic Technique to Probe Cell Deformability

Published on: September 3, 2014

施万细胞的节奏性收缩.

C M POMERAT

    Science (New York, N.Y.)
    |December 25, 1959
    PubMed
    概括
    此摘要是机器生成的。

    在大鼠背部根腺组织培养中的施万细胞表现出4到18分钟的收缩率. 这一发现与先前报告的在寡头质细胞中的活性相当.

    关键词:
    神经元/生理学

    更多相关视频

    Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films
    12:03

    Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films

    Published on: June 26, 2015

    Simplified, High-throughput Analysis of Single-cell Contractility using Micropatterned Elastomers
    14:33

    Simplified, High-throughput Analysis of Single-cell Contractility using Micropatterned Elastomers

    Published on: April 8, 2022

    相关实验视频

    Last Updated: Jul 9, 2026

    A Microfluidic Technique to Probe Cell Deformability
    09:47

    A Microfluidic Technique to Probe Cell Deformability

    Published on: September 3, 2014

    Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films
    12:03

    Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films

    Published on: June 26, 2015

    Simplified, High-throughput Analysis of Single-cell Contractility using Micropatterned Elastomers
    14:33

    Simplified, High-throughput Analysis of Single-cell Contractility using Micropatterned Elastomers

    Published on: April 8, 2022

    科学领域:

    • 神经科学是一个神经科学.
    • 细胞生物学 细胞生物学
    • 发展生物学 发展生物学

    背景情况:

    • 施万细胞是外周神经系统中负责髓化的质细胞.
    • 背部根腺含有感觉神经元及其相关的质细胞.
    • 了解质细胞的行为对于神经发育和神经系统疾病至关重要.

    研究的目的:

    • 为了在体外研究 Schwann 细胞的收缩活性.
    • 在组织培养中量化施万细胞的收缩率.
    • 为了比较施万细胞活动与其他质细胞类型,如寡合质细胞.

    主要方法:

    • 时间间隔摄影被用来观察细胞的行为.
    • 从新生小鼠身上准备了背部根结质组织培养物.
    • 随着时间的推移,测量了单个施万细胞的收缩率.

    主要成果:

    • 施万细胞表现出可测量的收缩率.
    • 观察到的收缩速度在大约4到18分钟之间.
    • 发现这种收缩活动的幅度与 oligodendroglia 报告的情况相似.

    结论:

    • 施万细胞在组织培养中表现出内在的收缩性质.
    • 施瓦恩细胞的收缩行为与寡头质细胞的收缩行为相似.
    • 这些发现有助于了解质细胞的动态和功能.