在高血压中平行心脏和血管适应
1Department of Medicine, New York Hospital-Cornell Medical Center, New York 10021.
Circulation
|December 1, 1992
概括
高血压会导致常见动脉的变化.
科学领域:
- 心血管医学 心血管医学
- 血管生物学 血管生物学
- 高血压研究 高血压研究
背景情况:
- 高血压的血管损伤有助于并发症.
- 有限的知识存在于动脉几何和功能在不复杂的高血压.
- 动脉变化与左心室缩之间的关系尚不清楚.
研究的目的:
- 为了研究活体动脉几何和功能在不复杂的高血压.
- 探索动脉变化与左心室缩之间的关系.
主要方法:
- 超声波评估了43名高血压和43名正常血压患者的常见动脉 (CCA) 壁厚和直径.
- 血管硬度估计来自动脉压力波形.
- 心声学评估左心室 (LV) 的大小和功能.
主要成果:
- 高血压患者显示LV和CCA壁厚度和LV质量增加.
- 28%的高血压患者患有动脉内心-中枢厚度增加.
- 在高血压患者中,尽管脉冲压力相似,但血管硬性显著增加.
结论:
- 无并发性高血压与CCA的几何和功能变化有关.
- 这些动脉变化与左心室观察到的平行变化相似.
- 这些血管变化对高血压中心血管并发症的贡献尚待确定.
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