在26名具有组织学上正常心周厚度的患者中,收缩性心周炎
Deepak R Talreja1, William D Edwards, Gordon K Danielson
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Circulation
|October 1, 2003
概括
狭窄性心膜炎可以发生在正常心膜厚度下,甚至在异常的显微镜检测结果下. 腹心切除术在缓解症状方面仍然有效,无论心周的厚度如何.
科学领域:
- 心脏病学 心脏病学
- 病理学 病理学 病理学
- 胸部外科手术 胸部外科手术
背景情况:
- 约束性心膜炎的诊断传统上依赖于心膜厚度的增加.
- 在收缩性心周炎中观察到非侵入性正常心周厚度,但缺乏临床病理学细节.
研究的目的:
- 在正常心周厚度的患者中研究狭性心周炎的临床病理相关物.
主要方法:
- 对143名因收缩性心周炎而接受心周切除术的患者的回顾性审查 (1993-1999年).
- 分析基线特征,操作数据和病原体样本.
- 分类为正常 (<或=2毫米) 和加厚 (>2毫米) 的心周组.
主要成果:
- 18% (26/143) 的患者心周厚度正常.
- 在正常厚度组的常见原因包括先前的手术,辐射,心脏病发作和异常疾病.
- 组织病理学在所有正常厚度病例中发现了轻微的焦点异常;心周切除术的结果在各组之间是相似的.
结论:
- 在狭性心周炎中,心周厚度并不总是增加的,尽管有焦点组织病理学异常.
- 对于疑似收缩的心力衰竭患者,不论非侵入性成像显示正常心周厚度,都应考虑进行心周切除术.
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