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由于缺乏可负担的抗毒素来治疗植物中毒而导致的死亡
Michael Eddleston1, Lalith Senarathna, Fahim Mohamed
1Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. eddlestonm@eureka.lk
Lancet (London, England)
|October 3, 2003
概括
在斯里兰卡,引入抗迪戈辛抗毒素显著减少了因树中毒造成的死亡人数. 它的撤回导致死亡人数增加了三倍,强调了发展中国家需要负担得起的抗毒素准入.
科学领域:
- 毒理学 毒理学 毒理学
- 药物经济学 药物经济学
- 全球健康 全球健康
背景情况:
- 发展中国家面临着负担得起的抗毒药和抗毒素的严重短缺.
- 中毒是严重的健康问题,特别是在有限的有效治疗方法的地区.
研究的目的:
- 为了评估抗迪戈辛抗毒素对香中毒病例死亡率的影响.
- 为了确定斯里兰卡的抗滴毒素抗毒素的成本效益.
- 倡导将中毒和中毒治疗纳入全球卫生倡议.
主要方法:
- 对抗毒素引入和取消之前和之后病例死亡率的回顾性分析.
- 成本效益分析将抗毒素的价格与其健康益处进行比较 (挽救生命,增加寿命).
主要成果:
- 引入抗迪戈辛抗毒素导致病例死亡率大幅降低.
- 取消抗毒素导致死亡率增加了三倍.
- 每个课程2650美元,每次生命节省的成本为10209美元,每年生命成本为248美元.
- 将价格降低到每课程400美元,将成本降低到每次获得的生命费用为1137美元.
- 将价格降至每疗程103美元将使治疗节省成本.
结论:
- 负担得起的anti-digoxin抗毒素对于管理树中毒和降低死亡率至关重要.
- 降低价格对于改善发展中国家的可访问性和成本效益至关重要.
- 将负担得起的中毒治疗方法与全球卫生运动相结合至关重要.
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