在HIV感染的男性中侵入性Haemophilus influenzae感染
R Steinhart1, A L Reingold, F Taylor
1Epidemiology Program, School of Public Health, University of California, Berkeley 94720.
JAMA
|December 16, 1992
概括
患有获得性免疫缺陷综合征 (艾滋病) 或人类免疫缺陷病毒 (HIV) 感染的男性面临侵袭性Hemophilus influenzae疾病的更高风险. 然而,这些感染在这个人群中仍然不常见,即使是b血清型.
科学领域:
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 侵袭性Hemophilus influenzae疾病对免疫系统受损的个人构成风险.
- 了解H. influenzae的发病率和血清型分布对于公共卫生战略至关重要.
研究的目的:
- 评估艾滋病或艾滋病毒感染的男性侵入性Hemophilus influenzae感染的发生率.
- 确定由H. influenzae血清型b.引起的这些感染的比例.
主要方法:
- 采用了基于人口的积极监测.
- 数据由旧金山卫生部收集.
- 这项研究包括20-49岁的男性,他们患有侵袭性H. influenzae疾病.
主要成果:
- 侵袭性H. influenzae疾病的累积发病率在艾滋病患者中为79.2 / 100,000,在没有艾滋病的HIV感染者中为14.6 / 100,000.
- 只有33%的侵入性H. influenzae病例是b型血清.
- 艾滋病患者和没有艾滋病的HIV感染者中,H. influenzae b疾病的发病率分别为每10万人中11.3和7.6.
结论:
- 艾滋病或艾滋病毒感染的男性患入侵性H. influenzae感染的风险较高.
- 尽管风险增加,但侵入性H. influenzae感染,包括血清型b,在这个人口中并不常见.
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