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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...

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相关实验视频

Updated: Jul 21, 2026

RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees (Apis mellifera)
10:57

RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees (Apis mellifera)

Published on: July 25, 2013

大脑中的基因表达特征可以预测蜜蜂个体的行为.

Charles W Whitfield1, Anne-Marie Cziko, Gene E Robinson

  • 1Department of Entomology, University of Illinois at Urbana-Champaign, 320 Morrill Hall, 505 South Goodwin Avenue, Urbana, IL 61801, USA.

Science (New York, N.Y.)
|October 11, 2003
PubMed
概括

蜜蜂大脑基因表达随着与年龄相关的行为变化而发生显著变化. 这些信使RNA (mRNA) 变化与食行为有关,而不仅仅是年龄.

科学领域:

  • 神经科学是一个神经科学.
  • 基因组学就是基因组学.
  • 动物行为 动物行为

背景情况:

  • 成年蜜蜂经历了与年龄相关的自然过渡,从内部蜂巢职责到外部食.
  • 了解衰老动物行为变化背后的分子机制至关重要.

研究的目的:

  • 研究成年蜜蜂大脑中的基因组变化,与过渡到食行为相关.
  • 为了确定观察到的基因表达变化主要是由年龄或行为驱动的.

主要方法:

  • 使用了72个微阵列的高度复制的实验设计来分析蜜蜂大脑中的信使RNA (mRNA) 丰富度.
  • 采用实验操纵来分离年龄和行为对基因表达的影响.
  • 开发了基于个体大脑mRNA配置文件的预测模型,以评估行为关联.

主要成果:

  • 在与年龄相关的行为过渡期间测试的约5500个基因中,在39%的mRNA丰度中观察到显著的变化.
  • 实验操作表明mRNA变化主要与食行为有关,而不是时间年龄.
  • 大脑mRNA概况准确地预测了60个蜜蜂中的57个蜜蜂的行为.

结论:

  • 成年蜜蜂大脑表现出广泛的基因组可塑性,与与行为转变相关的显著mRNA变化.

更多相关视频

Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees
13:55

Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees

Published on: July 21, 2014

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System
08:53

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System

Published on: September 6, 2016

相关实验视频

Last Updated: Jul 21, 2026

RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees (Apis mellifera)
10:57

RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees (Apis mellifera)

Published on: July 25, 2013

Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees
13:55

Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees

Published on: July 21, 2014

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System
08:53

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System

Published on: September 6, 2016

  • 行为,特别是寻找食物,是老化大脑中观察到的基因表达变化的主要驱动因素.
  • 个体大脑基因表达特征与蜜蜂自然发生的行为可塑性之间存在强烈的关联.