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Updated: Jul 19, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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在SCID-X1基因治疗后的两名患者中,LMO2相关的克隆T细胞增殖

S Hacein-Bey-Abina1, C Von Kalle, M Schmidt

  • 1INSERM Unit 429, Cedex 15, France.

Science (New York, N.Y.)
|October 18, 2003
PubMed
概括

使用逆转录病毒治疗X关联严重联合免疫缺陷 (SCID-X1) 的基因治疗取得了成功,但导致两名患者的T细胞增殖. 这与LMO2原瘤基因附近的逆转录病毒集成有关,导致不受控制的细胞生长.

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T Cell Activation and Clonal Selection

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