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Updated: Jul 19, 2026

High-resolution Spatiotemporal Analysis of Receptor Dynamics by Single-molecule Fluorescence Microscopy
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Published on: July 25, 2014

单个量子点跟踪揭示了甘氨酸受体的扩散动态

Maxime Dahan1, Sabine Lévi, Camilla Luccardini

  • 1Laboratoire Kastler Brossel, CNRS UMR 8552, Ecole Normale Supérieure and Université Pierre et Marie Curie, 24 rue Lhomond, 75005 Paris, France. maxime.dahan@lkb.ens.fr

Science (New York, N.Y.)
|October 18, 2003
PubMed
概括

半导体量子点 (QDs) 能够跟踪神经元膜中的甘氨酸受体 (GlyRs). 这揭示了GlyRs如何扩散到突触中,有助于我们理解神经元信号传递.

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Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...