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Updated: Jul 12, 2026

Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells
09:25

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Published on: August 19, 2016

李斯特菌的细胞内生长和毒性需要来自宿主的脂酸

Mary O'Riordan1, Marlena A Moors, Daniel A Portnoy

  • 1Department of Molecular and Cell Biology, School of Public Health, University of California, Berkeley, CA 94720-3202, USA. oriordan@umich.edu

Science (New York, N.Y.)
|October 18, 2003
PubMed
概括

李斯特菌需要酸蛋白联酶LplA1才能在宿主细胞内生长. 这种酶对于病原体的毒性至关重要,因为它的缺失在动物模型中显著降低了细菌的生存和感染力.

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