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Updated: Jul 13, 2026

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由HIV-1 Vif-Cul5-SCF复合体诱导APOBEC3G的无处不在和降解

Xianghui Yu1, Yunkai Yu, Bindong Liu

  • 1Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

Science (New York, N.Y.)
|October 18, 2003
PubMed
概括

人类免疫缺陷病毒-1 (HIV-1) Vif蛋白使用细胞Cul5-SCF复合体来降解抗病毒因子APOBEC3G. 这种相互作用对于病毒逃避至关重要,并为开发新的艾滋病毒疗法提供了潜在的目标.

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