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Updated: Jul 7, 2026

Evaluation of Keratinocyte Proliferation on Two- and Three-dimensional Type I Collagen Substrates
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Published on: April 22, 2019

其余脂蛋白诱导的光滑肌肉细胞增殖涉及表皮生长因子受体的转活

Akio Kawakami1, Akira Tanaka, Tsuyoshi Chiba

  • 1Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Building D-256, Bunkyo-ku, Tokyo 113-8519, Japan.

Circulation
|November 19, 2003
PubMed
概括

其余脂蛋白 (RLPs) 通过激活表皮生长因子 (EGF) 受体通路来促进光滑肌肉细胞 (SMC) 增殖. 这种机制涉及蛋白质激酶C (PKC) 和肝素结合EGF类似生长因子 (HB-EGF) 脱落,有助于动脉样硬化发展.

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