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Updated: Jul 27, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
09:14

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

不对称的,用一种新型的bis(phosphine) 氧化物奇拉连接剂合成alpha-chiral胺的催化合成

Alessandro A Boezio1, Julien Pytkowicz, Alexandre Côté

  • 1Département de Chimie, Université de Montréal, P.O. Box 6128, Station Downtown, Montréal (Québec), Canada H3C 3J7.

Journal of the American Chemical Society
|November 20, 2003
PubMed
概括

一个新型的配体,BozPHOS,使得从N-phosphinoylimines和dialkylzinc试剂中有效的铜催化合成α-chiral amines. 这种方法提供了高的产量和酶选择性,即使与较低的反应性二甲基,使用低的催化剂负载.

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