增强模块化聚基酸合成酶的模块化:在模块化聚基酸合成酶中进行晶化,其催化剂是malonyl-CoA:ACP晶酶

Pawan Kumar1, Andrew T Koppisch, David E Cane

  • 1Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.

概括

研究人员通过修改乙转移酶 (AT) 域来设计模块化多基化合成酶. 这种策略允许精确控制扩展器单元的结合,使新型聚胺天然产品类型的合成成为可能.

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