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Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
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使用分子动力学模拟的螺旋束蛋白质的初始折叠

Soonmin Jang1, Eunae Kim, Seokmin Shin

  • 1School of Chemistry, Seoul National University, Seoul 151-747, Korea.

Journal of the American Chemical Society
|December 4, 2003
PubMed
概括

使用隐性溶剂模型进行高温分子动力学模拟,可实现快速蛋白质折叠的模拟. 这种方法成功地预测了皮头部和A蛋白的本地结构,揭示了关键的早期折叠事件,如疏水性崩和螺旋体形成.

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