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对于SYCP3突变而异的患者的亚精子症

Toshinobu Miyamoto1, Shiga Hasuike, Leah Yogev

  • 1Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

Lancet (London, England)
|December 4, 2003
PubMed
概括

在SYCP3基因的突变破坏了精子生成,导致男性不孕. 一种特定的SYCP3突变损害了蛋白质相互作用和纤维形成,导致非阻塞性亚精.

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