内细胞和信号传递:在发育过程中的关系
Marcos González-Gaitán1, Harald Stenmark
1Max-Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany. gonzalez@mpi-cbg.de
Cell
|December 4, 2003
概括
细胞通过内细胞分裂将大分子内部化. 在"内细胞形成中的膜动力学"会议上提出的研究探讨了这种重要细胞过程的分子机制,受体信号传递,发育作用和病原体相互作用.
科学领域:
- 细胞生物学 细胞生物学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 内细胞分裂是所有真核细胞内部化宏分子的一个基本过程.
- 每两年举办一次的欧洲会议系列聚焦于前沿的细胞内膜瘤研究.
- 在意大利召开了2023年会议",内细胞分裂中的膜动力学".
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03:14Notch Signaling Pathway
The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule.
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
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Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
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