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Updated: Jul 27, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Published on: May 6, 2019

从瘤携带小鼠的T淋巴细胞中信号传导分子的改变

H Mizoguchi1, J J O'Shea, D L Longo

  • 1Biological Response Modifiers Program, National Cancer Institute, Frederick Cancer Research and Development Center, MD 21702.

Science (New York, N.Y.)
|December 11, 1992
PubMed
概括

瘤生长通过改变T细胞受体组件并减少关键信号分子来损害CD8+T细胞功能. 这项研究确定了导致癌症患者免疫缺陷的分子变化.

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