这个病人有肺栓塞吗?
Sanjeev D Chunilal1, John W Eikelboom, John Attia
1Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
JAMA
|December 6, 2003
概括
临床预测规则和经验丰富的临床医生的gestalt准确地评估肺栓塞预测概率. 预测规则被推用于较少经验的医疗保健专业人员的更广泛使用.
科学领域:
- 肺部医学 肺部医学
- 诊断的准确性 诊断的准确性
- 临床决策 临床决策
背景情况:
- 经验丰富的临床医生在估计肺栓塞预测概率时使用gestalt辅助.
- 临床预测规则与gestalt对于此评估的可比性尚不清楚.
- 临床预测规则可以赋予经验较少的专业人员在诊断肺栓塞方面的能力.
研究的目的:
- 为了比较临床gestalt与CPR在评估肺栓塞的预测概率方面的准确性.
- 评估CPR在简化PE诊断方面的实用性.
主要方法:
- 进行了对MEDLINE (1966-2003) 和文献资料的系统文献搜索.
- 研究包括连续的,未经选择的患者,医生对诊断测试结果视而不见.
- 涉及8306名患者的16项研究符合最终分析的纳入标准.
主要成果:
- 临床手术显示PE率为8-19% (低),26-47% (中等) 和46-91% (高) 的概率.
- CPR显示PE率为3-28% (低),16-46% (中等) 和38-98% (高) 的概率.
- 这两种方法在区分PE风险类别方面都显示出相似的准确性.
结论:
- 临床gestalt和CPR在按PE预试验概率对患者进行分层方面表现出可比的准确性.
- 由于其已被证明的准确性和适用性,CPR被不同经验水平的临床医生所倡导.
- 低预测概率 (通过CPR) 和负的D-二分体试验的组合可靠地排除PE.
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