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Updated: Feb 5, 2026

Author Spotlight: Unraveling the Impact of Mechanical Ventilation on Diaphragm Function and Patient Outcomes
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在早期小鼠胚胎中继承了先前无活化的父X染色体

Khanh D Huynh1, Jeannie T Lee

  • 1Howard Hughes Medical Institute, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

Nature
|December 9, 2003
PubMed
概括

哺乳动物的剂量补偿始于受孕时,一个X染色体 (X染色体) 已经在雌性胚胎中沉默. 这种父系X染色体表现出一个沉默梯度,挑战了以前对X失活时间的理解.

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