敌对行为预测了参与多重风险因素干预试验的男性心血管死亡率
Karen A Matthews1, Brooks B Gump, Kelly F Harris
1University of Pittsburgh, 3811 O'Hara St, Pittsburgh, Pa 15213, USA. matthewska@upmc.edu
Circulation
|December 10, 2003
概括
敌意与高风险男性的心血管疾病 (CVD) 死亡率有关. 高度的敌意,特别是在非致命的心血管疾病事件之后,显著增加了死于心血管疾病的风险.
科学领域:
- 心脏病学 心脏病学
- 心理社会因素 心理社会因素
- 公共卫生 公共卫生
背景情况:
- 敌意是冠心病的一个已知的危险因素.
- 它与高风险人群中心血管疾病 (CVD) 死亡率的关联仍未得到充分研究.
研究的目的:
- 在多重风险因素干预试验 (MRFIT) 参与者中评估16年来敌意和心血管疾病死亡率之间的关联.
- 检查敌意对在试验期间经历非致命心血管疾病事件的男性心血管疾病死亡率的影响.
主要方法:
- 通过结构化面试的回复,使用人际敌意评估技术来评估敌意.
- 分析了259名死于心血管疾病的男性和259名匹配的活体对照者的数据.
- 对包括血压,胆固醇,吸烟和之前非致命的心血管疾病事件在内的共变量进行控制.
主要成果:
- 高敌意的男性表现出明显更高的心血管疾病死亡率 (OR,1.61;95% CI,1.092.39).
- 在高敌意的男性中,心血管疾病死亡风险特别高,这些男性在试验期间经历了非致命的心血管疾病事件 (OR,5.06;95% CI,1.428.22).
结论:
- 敌意可能是高风险男性心血管疾病死亡率的重要风险因素.
- 专注于愤怒管理和压力减轻的干预措施,以及传统的风险因素修改,可以使敌对的患者受益.
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