在社区获得的肺炎
1Northeastern Ohio Universities College of Medicine, Rootstown, Ohio, and Infectious Disease Service, Summa Health System, Akron, Ohio, USA. filet@summa-health.org
Lancet (London, England)
|December 20, 2003
概括
由于抗微生物药物耐药性和新的病原体数据,成年人的社区获得性肺炎 (CAP) 管理正在发展. 及时的抗生素,适当的药物选择和疫苗接种是改善患者结果的关键.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 临床微生物学 临床微生物学
背景情况:
- 社区获得性肺炎 (CAP) 仍然是免疫能力强的成年人的重大健康问题.
- 肺炎链球菌 (Streptococcus pneumoniae) 新出现的抗微生物耐药性影响了实证治疗策略.
- 鉴定非典型病原体需要进一步研究它们的临床意义.
研究的目的:
- 审查有关CAP病因,临床过程,诊断,治疗和预防的当前信息.
- 突出与免疫能力强的成年人相关的管理问题.
- 讨论最近关于农业政策管理的指导方针建议.
主要方法:
- 审查当前的文献和最近的指南出版物关于社区获得的肺炎.
- 分析致病原体的新兴趋势,诊断方法和治疗策略.
- 讨论影响临床结果和预防方法的因素.
主要成果:
- 肺炎链球菌是主要的病原体,但耐药性正在增加.
- 不典型的病原体经常被确定,尽管由于诊断的局限性,它们的临床影响往往不清楚.
- 经验性抗微生物治疗仍然是标准的,以病原体谱和药理动力学/药理动力学原则为指导.
结论:
- 及时使用抗微生物药物,适当选择抗生素,并遵守临床途径,改善了CAP的结果.
- 对肺炎球菌病和流感的疫苗接种对于预防至关重要.
- 更新的指南为免疫能力强的成年人管理CAP提供了有价值的建议.
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