一种CPEB的神经元异型调节局部蛋白质合成,并稳定突触特异的长期促进aplysia

Kausik Si1, Maurizio Giustetto, Amit Etkin

  • 1Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, USA. ks560@columbia.edu

Cell
|December 31, 2003
PubMed
概括

在Aplysia细胞质中,多基化元素结合蛋白 (CPEB) 调节了在激活的突触处的局部蛋白质合成. 这种蛋白质对于长期突触促进的稳定维持至关重要,而不是其启动.