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Updated: Jul 15, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

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Published on: January 13, 2017

阐明在epotilone生物合成中cis双键形成的机制

Li Tang1, Shannon Ward, Loleta Chung

  • 1Kosan Biosciences, Inc., 3832 Bay Center Place, Hayward, California 94545, USA. tang@kosan.com

Journal of the American Chemical Society
|January 8, 2004
PubMed
概括

聚克化合成酶 (PKS) 酶复合物产生D和C等类表皮素.脱水酶域5 (DH5) 对于在这些化合物中产生12,13-cis-双键是必不可少的.

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