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Updated: May 13, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

通过DNA甲基转移酶的高频变异发生

J C Shen1, W M Rideout, P A Jones

  • 1Department of Biochemistry and Molecular Biology, Kenneth Norris, Jr., Comprehensive Cancer Center, University of Southern California, School of Medicine, Los Angeles 90033.

Cell
|December 24, 1992
PubMed
概括

甲基酶诱导DNA中的C到U突变. 这种酶是这种酶.

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Mismatch Repair

Overview
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Genome Copying Errors

DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base or a long stretch of wrong bases may get added to the daughter strands. If the errors are left unchecked, cells might accumulate several mutations that might endanger their  survival. Therefore, the copying errors are checked and repaired at three levels.
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Mismatch Repair

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