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Updated: Jul 6, 2026

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
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Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method

Published on: July 19, 2019

在二硫化物受约束的循环中,Xaa-Pro键的异常快速的 cis/trans 异构化

Tiesheng Shi1, Stephen M Spain, Dallas L Rabenstein

  • 1Department of Chemistry, University of California, Riverside, California 92521, USA.

Journal of the American Chemical Society
|January 22, 2004
PubMed
概括

酸中的循环二硫化物键意外地加速了 cis-trans 异构化,这表明了分子内催化. 这一发现为氧化还原酶活性位点的结构灵活性提供了洞察力.

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