潮湿的市场 - - 一个严重的急性呼吸系统综合征和流感的持续来源?
1Division of Virology, Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN 38105, USA. robert.webster@stjude.org
Lancet (London, England)
|January 24, 2004
概括
活体动物市场是新型病毒的潜在来源,如SARS冠状病毒和流感. 了解它们的生态学可以作为未来疫情的早期预警系统.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在亚洲普遍存在的活动物市场,出售各种动物,包括家禽,哺乳动物和爬行动物.
- 这些市场已涉及动物性疾病的传播,如H5N1禽流感和SARS冠状病毒.
- 尽管冷藏,但对活体动物的偏好仍然存在,增加了疾病传播的风险.
研究的目的:
- 调查活体动物市场作为动物传染病出现的潜在来源的作用.
- 探索湿市场中的生态因素,这些因素有助于病毒传播.
- 建立活体动物市场监督,作为潜在流行病的早期预警系统.
主要方法:
- 从喜马拉雅棕鸟中分离严重急性呼吸系统综合征 (SARS) 冠状病毒 (CoV) 并在犬中检测出血清学证据.
- 分析活禽市场内的疾病传播动态.
- 在潮湿市场监测病毒生态.
主要成果:
- SARS-CoV 从喜马拉雅棕鸟中分离出来,有证据表明熊狗和市场工人感染了SARS-CoV.
- 活禽市场被确定为H5N1禽流感向人类传播的来源.
- 这项研究支持了SARS动物源的假设,并强调了再次出现的风险.
结论:
- 活体动物市场对动物性病毒的出现和重新出现构成重大风险,包括SARS-CoV和流感.
- 了解这些市场的病毒生态对于开发有效的预警系统至关重要.
- 公共卫生战略应考虑加强活体动物市场的监测,以防止未来的疫情爆发.
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