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在患有不稳定胸痛的患者中随机选择药物或手术后,左心室细分壁运动的变化
M F Priest1, G C Curry, L R Smith
1Division of Cardiology, Department of Medicine, University of Alabama in Birmingham, University Station, Birmingham, Alabama 35294, USA.
Circulation
|September 1, 1978
概括
与医学治疗相比,冠状动脉再血管化手术显著改善了不稳定的心脏病患者的左心室 (LV) 壁运动. 在手术治疗的患者中,LV壁运动的改善与增强的冠状动脉输液相关.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 医疗成像医学成像
背景情况:
- 不稳定的胸痛带来了对心血管事件的重大风险.
- 评估左心室 (LV) 功能和冠状动脉输液对于管理不稳定的心脏病至关重要.
- 之前的研究强调了对医疗与外科手术干预的比较数据的需要.
研究的目的:
- 为了比较医疗与手术治疗对LV细分壁运动在不稳定的胸痛患者的影响.
- 为了研究LV细分壁运动变化和干预后冠状动脉输液之间的关系.
主要方法:
- 一项前性随机研究,涉及26名不稳定性胸痛患者.
- 双飞机左心室 (LV) 血管图和冠状动脉图 (CAG) 在基线和1年随访时进行.
- 数字计算机分析LV细分弹射率和LV细分冠状动脉输液的估计.
主要成果:
- 与医疗治疗相比,手术干预导致LV细分壁运动的改善更频繁.
- 在手术患者中,改善LV壁运动和增强冠状动脉输液之间观察到显著的相关性,特别是由左前下降动脉供应的段落.
- 在接受药物治疗的组中没有发现这种相关性.
结论:
- 冠状动脉再血管化手术可以在LV细分壁运动中提供优越的改善,与不稳定的心痛的医疗管理相比.
- 手术后改善的LV壁运动与增强的冠状动脉输液有关,特别是在左前下降动脉的领土上.
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