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Updated: Jul 25, 2026

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使用酸修饰表面对寡核酸微阵列的新方法

Guillaume Nonglaton1, Isa O Benitez, Isabelle Guisle

  • 1Laboratoire de Synthèse Organique, UMR CNRS 6513 and FR CNRS 2465, 2 Rue de la Houssinière, BP92208, 44322 Nantes Cedex 03, France.

Journal of the American Chemical Society
|February 5, 2004
PubMed
概括

这项研究引入了一种新的方法,用于使用酸衍生玻璃幻灯片创建寡核酸阵列. 这种方法显著增强了用于检测目标的光信号,提高了阵列性能.

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DNA Microarrays02:34

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...