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关于补充和替代医学研究的伦理问题
Franklin G Miller1, Ezekiel J Emanuel, Donald L Rosenstein
1Department of Clinical Bioethics, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Md 20892, USA.
JAMA
|February 6, 2004
概括
严格的伦理标准和随机试验对于评估补充和替代医学 (CAM) 疗法至关重要. 研究必须确保患者的安全,并科学验证CAM疗效,解决安慰剂效应.
科学领域:
- 医学伦理 医学伦理
- 综合医学研究 综合医学研究
背景情况:
- 补充和替代医学 (CAM) 的使用越来越多,需要对其安全性和有效性的研究.
- 尽管增加了研究,但CAM研究中的伦理考虑仍未得到充分解决.
- 公共卫生要求对CAM疗法的严格评估.
研究的目的:
- 突出CAM研究中的伦理要求.
- 在CAM临床试验中倡导标准化的伦理要求.
- 讨论安慰剂效应驱动疗法的伦理影响.
主要方法:
- 临床研究中的伦理原则的论证分析.
- 审查补充和替代医学现有研究实践.
- 探索随机,安慰剂对照试验方法来评估CAM疗效.
主要成果:
- 在CAM研究中,需要遵守与传统临床研究相同的伦理标准.
- 推随机,安慰剂对照试验来评估CAM有效性,如果可能的话.
- 当疗法仅仅由于安慰剂效应而有效时,就会出现道德挑战.
结论:
- 在CAM研究中坚持严格的伦理标准对于公共健康和安全至关重要.
- 标准化研究方法,包括随机对照试验,应应用于CAM.
- 使用仅通过安慰剂有效的疗法的伦理理由需要仔细考虑.
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