通过TLR7-介导的单链RNA的识别来进行先天性抗病毒反应

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Updated: Jul 21, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
12:47

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages

Published on: November 3, 2014

Sandra S Diebold1, Tsuneyasu Kaisho, Hiroaki Hemmi

  • 1Immunobiology Laboratory, Cancer Research UK, London Research Institute, London WC2A 3PX, UK.

Science (New York, N.Y.)
|February 21, 2004
PubMed
概括

这项研究揭示了托尔类受体7 (TLR7) 在内体内感知病毒RNA,触发干扰素的产生. 这种机制有助于天生的免疫细胞检测RNA病毒感染.

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