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Updated: Jul 20, 2026

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability
09:49

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability

Published on: April 2, 2015

一个膜蛋白中的Cαα-H...O键是不稳定的

Sarah Yohannan1, Salem Faham, Duan Yang

  • 1Department of Chemistry and Biochemistry, UCLA-DOE Center for Genomics and Proteomics, Molecular Biology Institute, 655 Boyer Hall, University of California, Los Angeles, Los Angeles, California 90095-1570, USA.

Journal of the American Chemical Society
|February 26, 2004
PubMed
概括

实验证据表明,calpha-H...O键并不能显著地稳定蛋白质. 在bacteriorhodopsin中突变一个关键残留物没有显示稳定性损失,这挑战了这些键在蛋白质结构中所扮演的角色.

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